Did you know that only about 30% of autoimmune disease is due to genetics?!
š»People often think of autoimmune disease as something they are destined to get if it runs in their family
š»Yet around 70% may actually be due to environment!
š»People who have one autoimmune disease are more likely to get others, however only a small part of this is due to DNA
š»Even if you have genetic markers for autoimmune disease, lifestyle factors can 'switch' these genes on or off (epigenetics)
š»The strongest evidence for lifestyle and autoimmune disease is around diet, smoking, alcohol intake, vitamin D, gut biome, obesity, exercise, and stress
š»Oestrogen also plays a strong role (80% of autoimmune disease occurs in women, there is a huge spike in autoimmune disease within a year of pregnancy, and rates drop significantly after menopause)
š»A diet high in saturated fat, added sugar (especially fructose), salt, and calorie dense foods are all linked with higher rates of autoimmune disease
š»Diets low in these, and high in whole plant foods and omega 3, reduce the risk
š»Fibre and antioxidants in foods seem to be the biggest factors - fibre feeds the gut biome and improves gut wall barriers (reduces 'leaky gut')
š»Ultra processed foods and emulsifiers can also increase risk of disease
š»Smoking is a known risk factor for many autoimmune diseases, as is excess alcohol
š»Obesity increases the risk of autoimmune diseases, due to several factors - increased inflammation, higher oestrogen levels, and effect on immune cells
š»Vitamin d deficiency is also strongly linked with an increased rate of autoimmune disease (vitamin d is involved in regulation of the immune system)
š»Regular exercise reduces the risk and severity of autoimmune disease, due to its effect on inflammation
š»Sleep deprivation and stress also have a very strong link with autoimmune diseases
š»Up to 80% of people report a significant stress shortly before autoimmune diagnosis
š» chronic sleep deprivation increases risk of autoimmune disease by up to 70% in some studies
š»In my next posts, I'll be discussing how you can both reduce these risks, and improve symptoms, with lifestyle
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5097114/
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